User Reviews for Tretinoin

Side Effects

Skin Care Tips- Treating HORMONAL ACNE

Retin a adult acne

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Chemically, tretinoin is all-trans-retinoic acid and has the following structure:. The safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established. RETIN-A Gel, Cream or Liquid should be applied once a day, before retiring, to the skin where acne lesions appear, retin a adult acne, using enough to cover the entire affected area lightly. The liquid may be applied using a fingertip, gauze pad, or cotton swab. If gauze or cotton is employed, care should be taken not to oversaturate it to the extent that the liquid would run into areas where treatment is not intended.

Application may cause a transitory feeling of warmth or slight stinging. In cases where it has been necessary to temporarily discontinue therapy or to reduce the frequency of retin a adult acne, therapy may be resumed or frequency of application increased when the patients become able to tolerate the treatment. Alterations of vehicle, drug concentration, or dose frequency should be closely monitored by careful observation of the clinical therapeutic response and skin tolerance.

During the early weeks of therapy, an apparent exacerbation of inflammatory lesions may occur. This is due to the action of the medication on deep, previously unseen lesions and should not be considered a reason to discontinue therapy. Therapeutic results should be noticed after two to three weeks but more than six weeks of therapy may be required before definite beneficial effects are seen. Once the acne lesions have responded satisfactorily, it may be possible to maintain the improvement with less frequent applications, or other dosage forms.

Patients treated with RETIN-A tretinoin acne treatment may use cosmetics, but the area to be treated should be cleansed thoroughly before the medication is applied. The skin of certain sensitive retin a adult acne may become excessively red, edematous, blistered, or crusted. If these effects occur, the medication should either be discontinued until the integrity of the skin is restored, or the medication should be adjusted to a level the patient can tolerate.

True contact allergy to topical tretinoin is rarely encountered. Concomitant topical medication, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices or lime should be used with caution because of possible interaction with tretinoin. Particular caution should be exercised in using preparations containing sulfur, resorcinol, or salicylic acid with RETIN-A.

If a reaction suggesting sensitivity or chemical irritation occurs, use of the medication should be discontinued. Exposure to sunlight, including sunlamps, should be minimized during the use of RETIN-A, and patients with sunburn should be advised not to use the product until fully recovered because of heightened susceptibility to sunlight as a result of the use of tretinoin. Patients who may be required to have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution, retin a adult acne.

Use of sunscreen products and protective clothing over treated areas is recommended when exposure cannot be avoided. Weather extremes, such as wind or cold, also may be irritating to patients under treatment with tretinoin.

RETIN-A tretinoin acne treatment should be kept away from the eyes, the retin a adult acne, angles of the nose, and mucous membranes. Topical use may induce severe local erythema and peeling at the site of application. If the degree of local irritation warrants, patients should be directed to use the medication less frequently, discontinue use temporarily, or discontinue use altogether. Tretinoin has been reported to cause severe irritation on eczematous skin and should be used with utmost caution in patients with this condition.

Long-term animal studies to determine the carcinogenic potential of tretinoin have not been performed, retin a adult acne. Studies in hairless albino mice suggest that tretinoin may accelerate the tumorigenic potential of weakly carcinogenic light from a solar simulator.

In other studies, when lightly pigmented hairless mice treated with tretinoin were exposed to carcinogenic doses of UVB light, the incidence and rate of development of skin tumors was reduced.

Due to significantly different experimental conditions, no strict comparison of these disparate data is possible, retin a adult acne. Although the significance of these studies to man is not clear, patients should avoid or minimize exposure to sun, retin a adult acne.

Oral tretinoin has been shown to be teratogenic in rats when given in doses times the topical human dose. Oral tretinoin has been shown to be fetotoxic in rats when given in doses times the topical human dose. Topical tretinoin has not been shown to be teratogenic in rats and rabbits when given in doses of and times the topical human dose, respectively assuming a 50 kg adult applies mg of 0.

However, at these topical doses, delayed ossification retin a adult acne a number of bones occurred in both species. These changes may be considered variants of normal development and are usually corrected after weaning. There are no adequate and well-controlled studies in pregnant women. Tretinoin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in human milk.

Because many drugs are excreted in human milk, caution should be exercised when RETIN-A is administered to a nursing woman. If medication is applied excessively, retin a adult acne, no more rapid or better results will be obtained and marked redness, peeling, or discomfort may occur. Oral ingestion of the drug may lead to the same side effects as those associated with excessive oral intake of Vitamin A. Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.

Although the exact mode of action of tretinoin is unknown, current evidence suggests that topical tretinoin decreases cohesiveness of follicular epithelial cells with decreased microcomedo formation.

Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion of the comedones. The effects of the sun on your skin. As you know, overexposure to natural sunlight or the artificial sunlight of a sunlamp can cause sunburn. Overexposure to the sun over many retin a adult acne may cause premature aging of the skin and even skin cancer. The chance of these effects occurring will vary depending on skin type, the climate and the care taken to avoid overexposure to the sun.

Therapy with RETIN-A may make your skin more susceptible to sunburn and other adverse effects of the sun, so unprotected exposure to natural or artificial sunlight should be minimized. When laboratory mice are exposed to artificial sunlight, they often develop skin tumors. These sunlight-induced tumors may appear more quickly retin a adult acne in greater number if the mouse is also topically treated with the active ingredient in RETIN-A, tretinoin.

In some studies, under different conditions, however, when mice treated with tretinoin were exposed to artificial sunlight, the incidence and rate of development of skin tumors was reduced. There is no evidence to date that tretinoin alone will cause the development of skin tumors in either laboratory animals or humans.

However, investigations in this area are continuing. Use retin a adult acne in the sun. An effective sunscreen should be used any time you are outside consult your physician for a recommendation of an SPF level which will provide you with the necessary high level of protection. For extended sun exposure, protective clothing, like a hat, should be worn. Avoid excessive exposure to wind or cold.

Extremes of climate tend to dry or burn normal skin. Your physician can recommend ways to manage your acne treatment under such conditions. The skin of certain sensitive individuals may become excessively red, swollen, blistered or crusted. There have been reports that, retin a adult acne, in some patients, areas treated with RETIN-A developed a temporary increase or decrease in the amount of skin pigment color present.

The pigment in these areas returned to normal either when the skin was allowed to adjust to RETIN-A or therapy was discontinued. Only your physician knows which other medications may be helpful during treatment and will recommend them to you if necessary.

In addition, you should avoid preparations that may dry or irritate your skin. These preparations may include certain astringents, toiletries containing alcohol, retin a adult acne, spices or lime, or certain medicated soaps, shampoos and hair permanent solutions. Do not allow anyone else to use this medication. The medications you have used in the past might cause unnecessary redness or peeling. If you are pregnant, think you are pregnant or are nursing an infant: If you are pregnant, think you are pregnant, or are nursing a baby, consult your physician before using this medication.

Use a mild, retin a adult acne soap. Avoid frequent washings and harsh scrubbing. Washing too frequently or scrubbing too roughly may at times actually make your acne worse. Wash your skin gently with a mild, bland soap.

Two or three times a day should be sufficient. Pat skin dry with a towel. Remember, excessive irritation such as rubbing, too much washing, use of other medications not suggested by your physician, etc. Forget about the instructions given for other products and the advice of friends.

Just stick to the special plan your doctor has laid out for you and be patient. There may be some discomfort or peeling during the early days of treatment. Some patients also notice that their skin begins to take on a blush. These reactions do not happen to everyone. These reactions can usually be minimized by following instructions carefully. Should the effects become excessively troublesome, retin a adult acne, consult your doctor.

If RETIN-A is going to have a beneficial effect for you, you should notice a continued improvement in your appearance after 6 to 12 weeks of therapy. Once your acne is under control you should continue regular application of RETIN-A until your physician instructs otherwise. All questions of a medical nature should be taken up with your doctor. Eastern Time, Monday through Friday.

You are encouraged to report negative side effects of prescription drugs to the FDA, retin a adult acne. Last reviewed on RxList: Adult Acne Slideshow Pictures. Test Your Acne IQ. Find Lowest Prices on. DRUG INTERACTIONS Concomitant topical medication, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices or lime should be used with caution because of possible interaction with tretinoin.

Carcinogenesis Long-term animal studies to determine the carcinogenic potential of tretinoin have not been performed. Pregnancy Teratogenic effects - Pregnancy Category C Oral tretinoin has been shown to be teratogenic in rats when given in doses times the topical human dose. Nursing Mothers It is not known whether this drug is excreted in human milk.

 

Retin a adult acne

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